![]() ![]() Less likely than warfarin to interact with other drugs or foods however, it does interact with some medicines.Crush one 2.5mg or 5mg tablet (depending on the dosage) and suspend in water, 5% dextrose in water, or apple juice, or mix with apple sauce and administer within four hours. A suspension may be made from the tablets for people who cannot swallow tablets whole. ![]() When given to prevent DVTs from forming after hip or knee replacement surgery the dosage is 2.5mg twice a day starting 12 to 24 hours after surgery.For people with at least two of the following: aged at least 80 years, body weight 60kg or lower, serum creatinine at least 1.5 mg/dL, then the dosage is 2.5mg twice daily. The recommended dosage for most people is 5mg twice a day. Apixaban is available as an oral tablet in two strengths (2.5mg and 5mg).However, the actual risk of major bleeding is low. An antidote was approved in 2018, called andexanet alfa.Apixaban is also used in the treatment of DVT and pulmonary embolism (PE) (where blood clots lodge in the lungs), and to lower the risk of recurrent DVT and PE.Also used to protect against the development of deep vein thrombosis (DVT) (blood clots in the deep veins) following hip or knee replacement surgery.Used to reduce the risk of stroke and blood clot formation in people with nonvalvular Atrial Fibrillation (AF).Apixaban belongs to the class of drugs known as factor Xa inhibitors.Through its action on FXa, apixaban makes blood less likely to clot. Apixaban works by selectively inhibiting (blocking) the effects of factor Xa (FXa), an enzyme that plays a key role in the formation of substances that cause blood clotting.Apixaban may be given to reduce the risk of blood clot formation.Medically reviewed by Carmen Fookes, BPharm. ![]()
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